The Latest:
Congratulations to Meghana Krishnan for completing her undergraduate degree at UCSD and moving on to pursue her PhD in Molecular Biology at Princeton University! (June 2025)
Congratulations to the skin regeneration group in collaboration with the Gur-Cohen lab for receiving the Sanford Stem Cell Institute Discovery Center Pilot Grant Award! (April 2025)
Welcome!
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At the heart of our research projects are Wnt proteins and their signaling pathways. Wnt genes encode a family of secreted lipid-modified growth factors (there are 19 Wnt genes in the mammalian genome) that regulate embryonic development and tissue homeostasis. Deregulated Wnt signaling impacts a large number of human diseases, including neurodegeneration and cancer.
In the Willert lab, we incorporate biochemical, genetic and cell biological approaches to study these proteins and their signaling cascades.